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For understanding side effects, see GLP-1 side effects
None of the approved GLP-1 or dual-agonist products carries a dermatologic indication, and the largest relevant real-world study, a target trial emulation with matched cohorts of 169,630 each, found no significant differences for inflammatory or autoimmune skin outcomes other than psoriasis, pemphigus and bullous pemphigoid after correction for multiple testing
The dysesthesia reported in trials, that unusual tingling or altered touch sensation, appears primarily at these higher doses
Asthma and respiratory conditions pose particular risks, especially with inhaled forms
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