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Common side effects of semaglutide include: Nausea Vomiting Diarrhea Stomach pain Decreased appetite Indigestion Belching Constipation Headache Semaglutide can cause serious side effects such as pancreatitis (inflammation of the pancreas), gallbladder problems, changes in vision, allergic reactions, and kidney issues

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One common mistake is stopping during the worst of the adjustment period, usually around days five through seven, and then restarting a week later

In these cases, it is best to link your injection to a specific, consistent anchor event, such as your first meal of the day or right before your longest sleep period

The UPenn study found fatigue ranked second among Reddit user complaints, suggesting it may be more common than trial data reflects