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Trends Cell Biol 28 , 237253, (2018)

Y.AnJ.MadhaniH

70 Thirty-three OA patients (mean age 60 years) were intra-articularly injected with four doses of BMP-7 or placebo

Furthermore, in transgenic mouse models expressing human -syn, hepatic -syn protein levels exhibit time-dependent accumulation despite the absence of -syn mRNA expression in the liver under neuron-specific promoter regulation, suggesting a potential neural system-derived origin of the protein [57]

Considering its wide use in many biological fields, we analyzed a relatively low dose of DMSO (0.1%, which is commonly applied in cell assays) to study the impact on the proteome, transcriptome and the epigenome

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