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The study, which tested the drug in 529 patients with obesity and heart failure with preserved ejection fraction (HFpEF), demonstrated a 16.6-point increase at 52 weeks, with regard to the Clinical Summary Score (CSS) on the Kansas City Cardiomyopathy Questionnaire (KCCQ) a measure of symptoms of heart failure in comparison to an 8.7-point increase in the placebo group
10.1016/j.bbagen.2012.10.005 Biochim Biophys Acta
doi: 10.1016/j.clim.2021.108714 12
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