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L-DOPA alone contributed to strong recovery of motion phenotypes during initial phase, however, its effect lagged in aged flies which showed movement defects similar to untreated park 13 mutants (Fig

Although prolonged appetite suppression with semaglutide might theoretically contribute to reduced nutrient intake, current evidence does not indicate a significant risk of specific micronutrient deficiencies, and the FDA has not identified micronutrient deficiency as a major safety concern in semaglutide approvals [28]

In some circumstances, a conditional marketing authorisation may be granted where the benefitrisk balance is positive but further confirmatory data are still awaited

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PubMed Central , Clinical, Cosmetic and Investigational Dermatology , vol