CAGRILINTIDE AND THE FUTURE OF GIP RESEARCH Cagrilintide represents a paradigm shift in appetite and obesity researchrepositioning GIP agonism as a primary mechanism for appetite suppression rather than merely a complementary approach to GLP-1 agonism
PENTADECAPEPTIDE AS BPC157,BODY PROTECTION PEPTIDE
Jordan, R., Carter, T
EBV glycoproteins: where are we now
Switching batches mid-experiment introduces a variable most protocols are not designed to absorb
What they found: 4,192 human genes change expression by 2 in response to GHK-Cu (31.2 % of the human genome) Of these 2,296 genes up-regulated , 1,896 down-regulated Pattern of changes: a rejuvenating signature, genes typically associated with ageing are down-regulated, regenerative genes up-regulated DNA repair , strong up-regulation of genes in BER, HR, NER pathways Mitochondrial biogenesis , increase in the number of mitochondria in cells Anti-apoptotic signal , protection against cell death Down-regulation of cancer signals , some oncogenes decreased Why it matters: This is the strongest evidence for the pleiotropic nature of GHK-Cu