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However, in diabetic wounds, the transition from M1 to M2 is disrupted, leading to the accumulation of M1 macrophages, which produce ROS and sustain long-term inflammation
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ME/CFS, FM, and GWS were selected for this review due to (i) the common overlap of ME/CFS and FM where similar biological dysfunction might be expected and (ii) GWS, with its identifiable and specific trigger, likely to offer a different biological perspective
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