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Chiu et al., 2013)
Significantly higher levels of xanthosine (Xant) and lower levels of G were seen in both patient groups compared to HC subjects
The GSSG is further recycled back to GSH by another cellular enzyme called glutathione reductase (GR) by using NADH as the reducing equivalent [8, 11,12,13,14,15,16,17,18]
If not otherwise indicated, detection of glutathione includes reduced (GSH) and oxidized (GSSG) glutathione
(PubMed) El-Gharbawy A, Vockley J
Since reactive oxygen species (ROS) primarily contribute to radiation-induced toxicity, antioxidant enzymes involved in ROS detoxification are expected to be influencing cellular radiosensitivity
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