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[18] [19] Report suspected side effects to medicines via the Yellow Card Scheme at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store

Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]

The resulting lipid peroxidation further damages hepatocytes, leading to inflammation and cell death

Free Radic Biol Med 30:11911212 Sideri M, Georgiou CD (2000) Differentiation and hydrogen peroxide production in Sclerotium rolfsii are induced by the oxidizing growth factors, light and iron

Medications and the risk of perforated appendicitis: an adverse event report system (FAERS) database analysis

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