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Overall, approximately 50% of all episodes of GI adverse events associated with Orlistat treatment lasted for less than 1 week, and a majority lasted for no more than 4 weeks
According to FDA prescribing information, the most frequently reported side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain
The glucose infusion rate was adjusted according to blood glucose levels until a first euglycemic steady state was reached (from ~70 to 100 min of infusion) and similarly adjusted until a second euglycemic steady-state was reached (from ~150 to 210 min of infusion)
While minor pain, tiredness, or nausea might occur shortly after the infusion, these symptoms typically resolve quickly
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