Most suffered from severe OSA, with mean AHI values of 50 events/hour
Guo JQ, Lin H, Lin F, Champlin R, Talpaz M, Kantarjian HM, Andreeff M , Zhao S, Glassman A, Arlinghaus RB
Before using any over-the-counter remedies including antiemetics, antidiarrhoeals, antacids, or herbal products always consult your trial team first, as some products may interact with the trial medicine or affect assessments
However, this prohibition includes exceptions for legitimate medical compounding that serves individual patient needs
Participants were asked not to wear contact lenses two days prior to the study visit, and no fluorescein, anesthetic, dilating or other ophthalmic drops were applied before sample collection
Other Safety Considerations Several additional safety topics are relevant to the clinical use of orforglipron: Gallbladder events: GLP-1 receptor agonists have been associated with increased rates of cholelithiasis and cholecystitis, likely mediated by rapid weight loss altering bile composition and gallbladder motility
