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Liraglutide (Saxenda): The Original Weight Loss GLP-1 Liraglutide was the first GLP-1 receptor agonist to receive FDA approval specifically for chronic weight management, doing so in 2014 under the brand name Saxenda

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Heres a quick guide to some of the most notable published and ongoing trials in the STEP series: STEP-1 is the first and largest STEP trial, involving 1961 nondiabetic but obese or overweight individuals

Will I receive additional weight loss support

Nausea, vomiting, or diarrhea

This change was part of an agreement reached last fall between the Trump administration, Eli Lilly and Novo Nordisk