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2013 Feb 1;9(1):33-54

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[1] [3] Patients with dietary deficiency and intact absorption may require less frequent injections or may be suitable for high-dose oral supplementation instead (typically 50-150 micrograms of cyanocobalamin daily between meals)

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Because body types vary, some people will lose weight faster than others, but in general, most people report losing about 2 to 3 pounds per week

Summary: Vitamin B12 supplements can be taken at any time of day, as absorption mechanisms function consistently throughout the 24-hour cycle, with consistency being more important than specific timing