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Exposure to GLP-1 RAs was consistently associated with significantly reduced odds of SUD cases

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Metabolic activation was provided using phenobarbital/benzoflavone-induced rat liver S9 (Moltox, Boone, NC) with added Regensys cofactors (Moltox, Boone, NC) at a final concentration of 1% S9

Retatrutide includes this pathway but does not rely on it exclusively

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Dual-diagnosis treatment offers an additional defense against relapse by treating mental illness and addiction symptoms simultaneously