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Antagonista GIP - agonista GLP-1: MariTida Este frmaco (Maridebart-cafraglutida o AMG133), que es un conjugado de un anticuerpo monoclonal frente al receptor de GIP y dos molculas de agonista del receptor de GLP-1, es eficaz en reducir el peso corporal en ratones y monos cinomolgus con obesidad

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Mechanism The GIP component is believed to contribute additional metabolic benefits beyond GLP-1 alone, including direct effects on adipose tissue metabolism and enhanced energy expenditure

Here are some additional considerations to guide your journey

Acute pancreatitis has been reported in clinical trials of tirzepatide, though the incidence is low, approximately 0.2 percent

Thats where a new wave of oral GLP-1 medications could make a difference