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[47] Acesulfame Potassium (Ace-K) - Paired with sucralose to create a more sugar-like sweetness profile and mask the slight bitter aftertaste either sweetener can produce alone

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J., Platten, M., Heiland, I., Trump, S., & Opitz, C

Retatrutide shows comparable HbA1c improvements in Phase 2 trials, but it lacks the comprehensive diabetes-specific trial data that tirzepatide possesses through the SURPASS program

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One commonly cited example is insulin, a naturally occurring peptide with a well-understood structure and function in glucose regulation, studied extensively in biochemical research