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However, NO is not universally detrimental

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moreover, acylcarnitine can be moved across plasma as well as intracellular membranes by specific transporters, shuttling the acyl groups among the different subcellular compartments to meet the metabolic needs (Indiveri et al., 2010)

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Dec 2017;58(3):448-457

Randomized controlled trials are underway, regulatory decisions lie ahead, and real-world data will continue to accumulate