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Pregnancy, Breastfeeding, and Family Planning Semaglutide must not be used during pregnancy or breastfeeding

It separately flags patients with renal or hepatic impairment, a diabetic history, or concurrent medications as needing special consideration

The first is that these improvements in mental health could be tied to the significant weight loss that usually comes from taking these medications

Novo Nordisk and its rival Eli Lilly have waged a two-horse race to dominate the anti-obesity market, with an eye toward expanding to patients who may feel uncomfortable with using an injectable drug

Three rules cover roughly 80% of muscle preservation on GLP-1 drugs: eat 1.6 to 2.0 grams of protein per kilogram of bodyweight per day, lift heavy 2 to 3 times per week, and keep weekly weight loss under about 1% of bodyweight