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Science 258 , 16621665 (1992)

While his colleagues in the aging field overwhelmingly stick to a safe script, describing their research as a quest to extend years of health, Sinclair talks freely and excitedly about extending mortality to 150 years by the end of the centuryto say nothing of death eventually becoming a rarityboth of which critics say there is zero science to support

Recent studies have demonstrated new anti-inflammatory properties for GLP1-R agonists

GLP-1RA can also affect the process of skin aging through interaction with advanced glycation end products (AGEs) and RAGE (receptors of AGEs) activation

Animal studies also tout promising results with acetyl-L-carnitine supplementation