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In contrast, the GLP-1R agonists disclosed herein are traditional small molecules that are orally bioavailable in standard formulations (e.g., methylcellulose) and have the potential to be combined with other oral small-molecule therapeutics
org/10.3390/jpm12071053 Pennisi, M., Lanza, G., Cantone, M., D'Amico, E., Fisicaro, F., Puglisi, V., Vinciguerra, L., Bella, R., Vicari, E., & Malaguarnera, G
Among them, Primary Immunoglobulin A Nephropathy (IgAN) is one of the leading causes of chronic kidney disease and kidney failure worldwide
Its antioxidant properties help to neutralize free radicals that are produced by UV exposure, which can help to reduce the risk of oxidative damage to the skin
Oxidative stress can damage blood vessels, leading to serious heart problems
Coord Chem Rev 322:3040 Yang J, Yang YW (2020) Metalorganic frameworks for biomedical applications
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