Yin C, Tang Y, Li X, Yang Z, Li J, Li X, et al
10.1016/j.jim.2020.112834 19 PathakG
NAD+ itself doesn't absorb well orally because of its molecular weight, which explains why most supplements contain precursors like nicotinamide riboside
Avoid overuse to prevent staining
The FDA approval is important, as we currently do not understand what the long-term health risks a patient may be putting themselves at risk of are
B12 shots bypass GI absorption problems and deliver methylcobalamin (the active form) directly to your cells, making them far superior to oral B12 if you have any digestive issues or take acid-blocking medications