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[1] [2] According to NICE guideline NG28 (Type 2 diabetes in adults: management), GLP-1 receptor agonists may be considered when metformin is contraindicated or not tolerated, or when other treatments have not achieved adequate glycaemic control, particularly in patients with a BMI 35 kg/m (or lower in certain ethnic groups) or when weight loss would provide additional clinical benefit

Patients also sometimes take drugs to alleviate swelling that occurs when the kidneys cant properly filter fluid, as well as medications to manage iron, calcium and vitamin D levels

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When to avoid injecting in the thigh The thigh is excellent for most people most of the time

They do not rely on the body to produce more GLP-1