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Estimands are defined as targets of estimation based on the trial objectives, providing greater transparency of the effects reported [60]

Medical Conditions That May Qualify You If your BMI is between 27-29.9, you may still qualify for GLP-1 medications if you have: Type 2 diabetes or prediabetes High blood pressure (hypertension) High cholesterol or dyslipidemia Sleep apnea Cardiovascular disease Metabolic syndrome Insulin resistance These conditions are often interconnected with weight, and GLP-1 for weight loss can help address multiple health concerns simultaneously

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Estrogen therapy has been associated with improved insulin sensitivity, reduced central fat distribution, and enhanced quality of life (Santen et al., Menopause, 2020)