These are classified as acquired lesions, namely not genetic based (within reason, exceptions include genodermatoses)
In this paper, we extend our most recent model [20] to include cysteine and glutathione metabolism (Figure 1)
In endometrial cancer, autocrine hGH enhances the oncogenic characteristics in vitro and promotes the growth of RL95-2 tumors when GHR is overexpressed in vivo (Pandey et al., 2008)
JAMA Internal Medicine, 173 (5), 355-361
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This is especially concerning for humans, as the molecular signalling in human disease is far more complex than in many animal models ( Figure 2 schematizes the two faces of lipid peroxidation