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Curcumin exerts a protective effect against premature ovarian failure in mice

Ma et al

Hyperglycemia, hyperinsulinemia, or hypoinsulinemia can cause oxidative stress, and reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced by excessive oxidative stress can disrupt the BBB and further affect central nervous system (CNS) function

10.1007/s10534-013-9610-x 61 YokoyamaS.TanakaY.NakagitaK.HosomiK.TakadaM