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2003/04, Gezondheidsraad, (Dutch National Health Counsel) Den Haag 2003: 130-31 2
The onset of symptoms is in the first months or years of life
In particular, ROS affects T cell receptor signaling through several downstream signaling pathways (57, 61, 62), including mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinases (PI3K), and Janus kinase-signal transducer and activator of transcription 3 (JAK-STAT3)
Diabetes Care, 46 , 384390
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In such patients, the ADA-EASD 2022 consensus report also recommends the combination of GLP-1RAs and SGLT2is when hemoglobin A1c (HbA1c) target is not reached with a drug from one of the two classes [6]
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