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In a 2023 Business Insider interview, Dr Frank shared "I think a combination of age and the rapidity of the weight loss is what's causing what I call Ozempic face.When you meet someone that you saw not too long ago and they've lost a lot of weight, it's kind of like a telltale sign." Just as the stories of Ozempic-aided weight loss took over social media came the horrifying images of Hollywood celebrities who had gone too far and were looking skinny and haggard after excessive weight loss

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