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Inhibition of CYP450 enzyme activity and activation of the Nrf2 signaling pathway and GSH synthesis are two intriguing targets for the treatment of acute liver injury caused by APAP

Marso SP, McGuire DK, Zinman B, Poulter NR, Emerson SS, Pieber TR, et al

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In view of these important functions, carnitine is increasingly detectable, particularly in tissues such as the skeletal and cardiac muscles, which use fatty acids as a food fuel