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SPL UNCLASSIFIED SECTION Hypersensitivity Reactions In a pool of Study 1 and 2, immediate hypersensitivity reactions (within one day after drug administration) occurred in 2.1% of ZEPBOUND-treated patients compared to 0.4% of placebo-treated patients, while non-immediate hypersensitivity reactions occurred in 3.5% of ZEPBOUND-treated patients compared to 2.7% of placebo-treated patients

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GH secretagogues begin amplifying growth hormone pulses, but the downstream effects on fat metabolism take time to accumulate

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The copper chelation appears to facilitate cellular uptake through copper transport proteins expressed in keratinocytes and fibroblasts

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NA, Not Applicable (for relevant criterias)

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