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Angiogenesis concern: Because GHK-Cu promotes blood vessel formation, there is a theoretical concern that it could support tumor vascularization in individuals with active cancer

Lau, J., Bloch, P., Schffer, L., Pettersson, I., Spetzler, J., Kofoed, J., Madsen, K., Knudsen, L.B., McGuire, J., Steensgaard, D.B., Strauss, H.M., Gram, D.X., Knudsen, S.M., Nielsen, F.S., Thygesen, P., Reedtz-Runge, S., & Kruse, T

Copper toxicity concerns exist with prolonged GHK-Cu use, though clinical cases remain extremely rare at therapeutic doses

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Researchers should also document preparation details and monitor storage conditions to support consistency between laboratory studies