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A commensal Bifidobacterium longum strain prevents gluten-related immunopathology in mice through expression of a serine protease inhibitor

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Mucolytics such as dornase alfa (NCT04402944, phase II of recombinant human DNase I for COVID-19) and mannitol (NCT00251056, phase II of mannitol for cystic fibrosis) have been tested mainly to relieve mucus blockages, but they do not assist drugs breakthrough or controllability interact with the mucus effectively

When inhibiting enzymes in the gastrointestinal tract, it is swiftly biotransformed (half-life 3.0.CO;25 41 OosthuizenCBReidAMLallN

npj Viruses 3 , 27 (2025)