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Tirzepatide at the highest dose produced even more dramatic results, with average weight loss reaching 20.2% in the SURMOUNT-5 trial

By targeting NNMTan enzyme highly expressed in adipose tissue and linked to insulin resistancethis compound allows researchers to explore how shifting cellular metabolism away from fat storage toward energy utilization can impact systemic health

More rarely, severe side effects such as severe nausea, vomiting, pancreatitis, or gallbladder inflammation may occur

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