Here are some of the benefits we are seeing: Improved blood sugar control Increased insulin sensitivity Lowered risk of nerve damage and kidney disease (this is most pertinent for diabetic patients) Lowered cholesterol levels Lowered blood pressure levels Decreased risk of stroke Decreased risk of cardiac events (like a heart attack or heart disease) Its important to point out that most of these benefits are a result of losing weight (we see these benefits after bariatric surgery as well) but some studies are showing positive benefits on their own (regardless of the amount of weight loss)
In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions
In murine erythroleukemia (MEL) cells, AIFM2 did not affect apoptotic status but instead promoted erythroid differentiation 41
Retatrutide's 28.7% at 68 weeks closes a two-decade arc that began with every major pharma trying to shut the glucagon receptor off
If you experience any suspected side effects from either medication, report them via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)
The effect is most noticeable after eccentric exercise like downhill running or heavy resistance training