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The strongest rationale for the oral route is local action in the digestive tract itself
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Neuroprotection Research: Emerging gut-brain axis investigations: pro-inflammatory cytokine reduction in hippocampus, neuronal integrity preservation after trauma, dopaminergic and serotonergic system interactions, behavioral studies in rodent models
Others, like correction of anemia or nerve symptoms, might take a few weeks of consistent therapy
This titration approach helps identify your personal tolerance
L. I. Fedoreyeva, T. A. Smirnova, G. Ya. Kolomijtseva, V. Kh. Khavinson, and B. F. Vanyushin, Interaction of short peptides with FITC-labeled wheat histones and their complexes with deoxyribooligonucleotides, Pleiades Publishing Ltd, Feb. 2013. doi: 10.1134/s0006297913020053
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