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We used a Mendelian randomization design to test whether this relation might be causal

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Helps Overcome Fatigue Fatigue is a common symptom of B12 deficiency

Signs and symptoms of vitamin B12 deficiency signs may include: Weakness or fatigue Pale skin Appetite loss Weight loss Palpitations Numbness and tingling Poor concentration Infertility Depression Memory impairment Sore mouth or tongue Disturbed sleep Frequent infections What are the side effects of a B12 shot