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Genetics: Some people respond better to certain medications due to genetic makeup

Options that many people find well tolerated include: Boiled or mashed potato (without heavy cream or butter) White rice or plain pasta in small quantities Soft-cooked vegetables such as courgette, carrots, and spinach Porridge oats are nutritious but contain moderate fibre

Domnguez R, Pagano M, Marschoff E, Gonzlez S, Repetto M, Serra J

Starting biologics early, before significant spinal fusion occurs, produces the best outcomes

Diabetes Care (2022)

Thus, increased insulin resistance may decrease the serotonergic neurons responsiveness to estradiol