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Figure 3: Chemical structures of Nle1-AngIV (Nle-Tyr-Ile-His-Pro-Phe) and Dihexa (N-hexanoic-Tyr-Ile-(6) amino hexanoic amide)

BPC-157 has a short elimination half-life under 30 minutes following injection, meaning the peptide rapidly enters circulation and distributes to tissues

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This manuscript represents the first study of combination DPP-4 inhibitor and once-weekly GLP-1 RA therapy