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Weight management success depends primarily on caloric intake, physical activity, and hormonal regulation

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It is important to note that while preliminary evidence is encouraging, the combination is not a substitute for comprehensive PCOS management, which should include lifestyle modifications such as regular physical activity, balanced nutrition, and weight management when appropriate

In this systematic review, we aimed to characterise the trajectory of weight regain after GLP-1RA cessation

In addition, success depends largely on the willingness of GLP-1 users to permanently change their behavior (regular intake, eating habits, exercise)