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And reduction rate between (-5.6,-6.7 mm Hg) in a 26 week study of liraglutide in combination with Metformin and Rosiglitazone compared to (-1.1 mm Hg)placebo and also with no difference in diastolic blood pressure [12]
This mechanism stimulates insulin release and slows gastric emptying
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For broader literature on potential harms in related contexts see this review at PMC
And that has its own domino effect
GLP-1 treatment led to ~20% lean mass loss
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