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triple or multi-receptor agonists are forecast to expand at a 32.25% CAGR to 2031

Following relevance-based screening, approximately 20 to 35 studies were included in the final narrative synthesis

The peptide's remarkable stability in gastric juice allows for oral administration in research settings, making it unique among therapeutic peptides

Tirzepatide acts on both GLP-1 and GIP receptors

In Hashimoto's disease, immune-mediated inflammation gradually impairs the gland's ability to synthesise and release these hormones

Two randomized controlled trials in women with hypothalamic amenorrhea have shown conflicting results: one indicated an increase in osteocalcin and N-telopeptides of type 1 collagen (NTX) but no change in BMD [102], while the other revealed increased spine BMD in lean women with hypoleptinemia [101, 103, 104]