Adding to all that is dealing with weight gained during pregnancy
Endocr Pract 22 , 12771287, (2016)
Does intestinal dysbiosis contribute to an aberrant inflammatory response to severe acute respiratory syndrome coronavirus 2 in frail patients
In Phase 2 clinical research, retatrutide demonstrated body weight reductions of up to 24.2% over 48 weeks, the largest reported for any incretin-based compound at that stage of development [8]
These enzymes form a multienzyme metabolic complex, which translocates to the nucleus during S (DNA replication) and G2/M (DNA damage checkpoint) phases, and is required for biosynthesis of the nucleotide precursor, thymidylate, which is critical to DNA synthesis and repair
Additionally, a newer medication called Mounjaro (tirzepatide) has been shown to provide impressive reductions in A1C and weight