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In this part of the study, the authors demonstrated the GLP-1R was expressed in mural granulosa cells (MGCs), and its expression was decreased in the PCOS model

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Excess body fat produces estrogen

doi: 10.1038/oby.2009.510CrossRefGoogle ScholarPubMed Moaddel, R., Shardell, M., Khadeer, M., Lovett, J., Kadriu, B., Ravichandran, S., Zarate, C

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Lipid -oxidation: As a result of lipid accumulation, -oxidation of fatty acids by cytochrome P450 enzymes has occurred and generated ROS