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The peptide is engineered with a fatty-acid moiety to extend its circulation time (half-life ~6 days), allowing for once-weekly dosing [2]
The TRIUMPH-CVOT cardiovascular outcomes trial will provide longer-term safety data
Dovizio, M., Maier, T
One factor to consider is how quickly you've lost weight
It is unlikely that the manufacturers of this class of medicines imagined that PPIs would be linked to fractures
If the powder still has not dissolved after refrigeration, the peptide may have been damaged during lyophilization or shipping, rendering it partially insoluble
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