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Constipation is the most persistent side effect, affecting roughly 15 to 20 percent of long-term users, and often responds to increased fiber intake and hydration

Additionally, a maintenance dose may be necessary in the long term

Get Enough Sleep: Aim for 7-9 hours of quality sleep per night to support natural repair and detoxification processes, as lack of sleep can rapidly deplete glutathione

Tips for managing side effects when switching If you switch GLP-1 medications, you may experience gastrointestinal side effects such as nausea, diarrhea, stomach pain, appetite reduction, constipation, bloating, and excessive burping

124 GLP-1, by activating its receptor, increases insulin secretion and reduces glucagon secretion, thereby lowering blood sugar levels

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