oral semaglutide cardiovascular outcomes soul trial results 2024 2025 Updates in Medicine on X: "SOUL (NEJM 2025): led to a 14% ↓ in major CV events vs placebo in T2DM with ASCVD or CKD — no ↑ in soul trial oral semaglutide cardiovascular

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Weeks 9 through 16: therapeutic dosing Moving to 1.0mg and eventually 1.7mg per week represents the therapeutic range where semaglutide produces its most significant effects

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One part of this combo (CJC-1295) binds a pituitary receptor to stretch out and strengthen each natural pulse of growth hormone

A fixed-effect model was used for meta-analysis where heterogeneity was less than 50%

Ginger tea, ginger chews, and peppermint have modest evidence for nausea relief