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A nested casecontrol design is efficient for evaluating relatively uncommon outcomes (I.e.,substance use disorder) within a large cohort and supports clear temporality between exposure and outcome through index-date anchoring and matching
Beyond glycemic control in diabetes mellitus: effects of incretin-based therapies on bone metabolism
In hepatocytes, SREBP2 activation increased HMGCR transcription, but ALC reverses this trend
HF-related outcomes: GLP-1 RAs showed a trend toward a reduced risk of hospitalization for heart failure (HF)
Front Cell Dev Biol (2021) 9:690306
TMAO is predominantly sourced from choline (found in foods such as red meat, fish, poultry, and eggs) and metabolized by microbiota to TMA and then to TMAO through the action of the hepatic enzyme, flavin monooxygenase 3 (FMO3) (8)
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