Data representative of three independent experiments and the K d values calculated as the arithmetic mean and the standard deviation of the mean
NE C should be used in pregnant women only if clearly necessary
Frequently Asked Questions Weve laid out the similarities and the differences between GLP-1, GLP-2, and GLP-3, now lets answer some other common questions
They work when the protocol supports them
Compounded medications are not FDA-approved and do not have equivalent clinical trial data establishing the same safety, efficacy, or outcomes
| Parameter | Orforglipron (oral pill) | Retatrutide (injectable peptide) | | --- | --- | --- | | Molecular class | Non-peptide small molecule | Peptide (amino acid chain) | | Receptor profile | GLP-1 (single target) | GIP + GLP-1 + glucagon (triple) | | Administration | Oral, tablet | Subcutaneous injection | | Interval | Once daily | Once weekly | | Half-life | Short (daily dosing) | approx