By dosage, the mean changes were: 500 mcg: 127% 750 mcg: 176% (single study) 1,000 mcg: 280% 1,500 mcg: 310% 2000 mcg: 260% 5,000 mcg: 62% While 1,500 mcg of vitamin B12 showed the highest average increase, the effect plateaued or declined at higher doses, suggesting a possible saturation of absorption pathways
J., Blake, J
But if you feel tired or have stomach problems, you might want to rest for a few hours until those symptoms go away
Nerve cell damage in the brain causes dopamine levels to drop, leading to the symptoms of Parkinsons
The degradation routes do not even belong to the same branch of chemistry: the peptides degrade by hydrolysis, isomerization and oxidation, while the copper complex changes by ligand exchange, by reduction of the metal, and by displacement of copper by any competing binder that reaches it
Medical Review Status Last reviewed: June 2026 | Next review: December 2026 Written by Dr