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Piperlongumine Piperlongumine (PL) is an alkaloid isolated from Piper species, commonly used in traditional medicine in particular in Asia and Latin America that in recent years has been extensively studied because of its anti-cancer potential, being able to inhibit proliferation in several cancer cell lines 107

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However, factors such as aging, stress, and environmental pollutants can cause its levels to deplete, leading to dull and uneven skin tone

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Please note I am not a medically trained person but I've had Pernicious Anaemia (just one of many causes of B12 deficiency) for more than 47 years and still treated with cyanocobamalin 1mg injections now every three weeks

Without the sodium, magnesium, calcium, and other minerals in the water, it will have a flat and bland taste