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Its ~6-day half-life is achieved via a C20 fatty diacid moiety that promotes albumin binding, slowing clearance and protecting the peptide from enzymatic degradation

A 2022 meta-analysis found green tea polyphenols may improve insulin sensitivity and fasting glucose, but did not measure GLP-1 directly

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily licensed for the management of type 2 diabetes mellitus and, more recently, for weight management in adults with obesity or overweight with weight-related comorbidities

doi: 10.1016/S0140-6736(19)31150-X 6 SterneJACSavovicJPageMJElbersRGBlencoweNSBoutronIet al

Five stages of evolving -cell dysfunction during progression to diabetes